Natural Products Insider

MAR-APR 2019

INSIDER is the leading information source for marketers, manufacturers and formulators of dietary supplements, healthy foods and cosmeceuticals. Since 1997, INSIDER has been serving the needs of the global nutrition industry.

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Clinically shown to boost nitric oxide production 1 40+ claims supporting energy, focus, cognitive function & more 1-5 Prevents the decline in cognitive function that occurs following strenuous exercise 2 Enhances mental flexibility, processing speed, & executive functioning after a single dose 3,4 Rapidly increases mental acuity & focus in as little as 15 minutes 3 25+ studies supporting efficacy & safety GRAS-affirmed at clinically substantiated doses, with FDA New Dietary Ingredient (NDI) notification status Easy to formulate into ready-to-mix powders & tablets, nutritional bars, RTD's, & energy drinks Learn more about Nitrosigine's clinically substantiated claims at: www.Nutrition21.com info@Nutrition21.com *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. 1. Kalman D, Feldman S, Samson A, Krieger D. A clinical evaluation to determine the safety pharmacokinetics and pharmacodynamics of an inositol stabilized arginine silicate dietary supplement in healthy adult males. Clin Pharmacol. 2015;7:103-109. 2. Evans M, Zakaria N, Marzuk M, Perez Ojalvo S, Sylla S, Komorowski J. An evaluation of the effects of inositol-stabilized arginine silicate (ASI; Nitrosigine ® ) in preventing the decline in cognitive function caused by strenuous exercise. J Int Soc Sports Nutr. Date TBD 2018. 3. Kalman D, Harvey P, Perez Ojalvo S, Komorowski J. Randomized prospective double-blind studies to evaluate the cognitive effects of inositol-stabilized arginine silicate in healthy physically active adults. Nutrients. 2016;8(11):736. 4. Kalman D, Hewlings S, Sylla S, Perez Ojalvo S, Komorowski J. An evaluation of the effects of inositol-stabilized arginine silicate (ASI; Nitrosigine ® ) on cognitive flexibility. J Int Soc Sports Nutr. Date TBD 2018. 5. Rood-Ojalvo S, Sandler D, Komorowski J. The benefits of inositol-stabilized arginine silicate as a workout ingredient. J Int Soc Sports Nutr. 2015;12(Suppl 1):P14. ©2018 Nutrition 21, LLC Nitrosigine is a registered trademark of Nutrition 21, LLC. Nitrosigine is protected by a number of patents and pending patent applications on compositions, their manufacture, and/or their uses, including, but not limited to: U.S. Patent Nos.: 6,803,456 and 7,576,132. DRA1649101218

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