Natural Products Insider

MAY-JUN 2019

INSIDER is the leading information source for marketers, manufacturers and formulators of dietary supplements, healthy foods and cosmeceuticals. Since 1997, INSIDER has been serving the needs of the global nutrition industry.

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18 INSIDER May /June 2019 training may be insuffi cient to allow a reduction of tissue stress damage," said Shaheen Majeed, president worldwide for Sabinsa. "The general consumer is fi nally starting to get the idea that recovery is necessary and while they sift through the rhetoric, they are slowly grasping concepts that scientists (and formulators) have been trying to educate over the years," Sandler added. Sports nutrition expert Sue Hewlings, Ph.D., R.D., director of scientifi c affairs for Nutrasource and co-founder of Substantiation Sciences, said recovery is an overlooked part of sports nutrition, especially by active consumers and weekend warriors. In her presentation at SupplySide East 2019, she said one issue is the challenge in defi ning recovery, which involves limiting damage from exercise and preparing the body for the next workout. However, she noted recovery goes beyond the one- or two-hour post-exercise window and is more of a 24/7 necessity. She outlined many aspects of recovery that brands can target, including peripheral (muscle glycogen) and central (neuromuscular) fatigue, hydration (electrolytes), nutrition (glycogen depletion), muscle soreness/weakness, exercise performance, increased infection risk, gastrointestinal (GI) abnormalities, quality and quantity of sleep, and infl ammation— some infl ammation is good. Hewlings highlighted curcumin as a well-researched anti-infl ammatory botanical ingredient to inhibit infl ammatory signaling and muscle damage. Several other botanicals shown to offer some combination of reducing infl ammation, limiting muscle damage, decreasing delayed onset muscle soreness (DOMS) and improving muscle function include black currant, cherry, pineapple, pomegranate, watermelon, cucumber extract, beet root and astaxanthin (a carotenoid from algae). She also touted specialty ingredients omega-3 fatty acids and MSM (methylsulfonylmethane). Majeed also singled out curcumin and beet root. He noted betalains present in Sabeet ® beet root extract (from Sabinsa) were shown to infl uence infl ammatory markers such as c-reactive protein (CRP) to help manage infl ammation and improve exercise performance (Int J Innov Res Med Sci. 2016;1(9):376-383). He further noted in addition to anti-infl ammatory effects, curcumin (as CurcuminC3 Complex ® ) may have a prebiotic-like benefi t that helps foster proper conditions for benefi cial microbiota growth, which may help both GI and immune areas of recovery. Another digestive approach is with enzymes that improve macronutrient digestion, including amylase (for carbs), lipase (for fats), proteases (for protein) and cellulase (for cellulose). Majeed noted a blend of such enzymes (as DigeZyme ® , from Sabinsa) may improve DOMS, which is driven by infl ammation. In one study, these non-animal enzymes improved subjective pain and muscle tenderness following eccentric exercise (Sports Nutr Ther. 2016;1-3). DOMS may also have an immune factor, according to Majeed. "The immune system is not able to function fully during periods of high physical stress, possibly by down- regulating immune and endothelial function, which could result in a reduced capacity to metabolize any damaged muscle cells," he explained. One hot ingredient bound to impact sports nutrition and active consumers is cannabidiol (CBD), which plays a role in immune-mediated infl ammation. Hewlings explained the body's endocannabinoid system has a physiological role in the functions of immune cells involved in infl ammation. CBD and other endocannabinoids that target the CB2 receptor offer potential anti-infl ammatory benefi ts that could help in exercise recovery. Kneller said if he were asked to formulate a product for active consumers, he'd consider a CBD supplement for recovery. "A CBD 'candy' or edible for post-workout would be a hot item," he assured. "I'm very confi dent we will see a large amount of CBD stuff in single-serve pack-outs for this crowd." For improved performance, especially indirectly via accelerated recovery, Almada pointed to quercetin, which he called the predominant fl avonoid in the diet subject to many human studies for over 15 years. "However, as with virtually all dietary/ ingestible interventions, the biological response is largely related to the absorption and bioavailability of what is consumed," he said, noting quercetin absorption has been shown to vary widely among persons, by up to 50 percent. Indena applied its Phytosome More Bioavailable ® delivery system technology to this very water-insoluble fl avonoid to yield Quercefi t™. An open label study of amateur sprint triathletes showed two weeks of Quercefi t supplementation decreased sprint distance times by around 11 minutes, compared to a four-minute decrease among the control group. (Minerva Medica. 2018;109:285-9.) "Additionally, subjective recovery scores and blood markers of oxidative stress were signifi cantly improved in the Quercefi t group," Almada noted. Sports Nutrition for All Despite the many instances of overlap, active consumers and weekend warriors have different needs and desires than do elite amateur and pro athletes. For some brands, the active consumer group represents an opportunity to have a play in sports nutrition. For legacy sports nutrition brands, this is an opportunity to spread the proverbial formulation wings. While banned substance certifi cation might be primarily for drug-tested athletes including collegiate, Olympic and professional, the desire to know what is in a nutrition product cuts across the entire sports nutrition market. "All consumers—but mostly the active consumer/weekend warrior/intelligent business person/concerned housewife— want to know what it is in the product," Sandler said, emphasizing the importance of transparency and quality control (QC). "Even this consumer is beginning to stack products, and while they may not realize they are doing it, I think they are understanding that single products can only do so much; depending on their goals, they need a few things, and transparency helps solve that." Brands can consider many ingredient, marketing and labeling messages when targeting active consumers and weekend warriors. Protein and energy-boosting ingredients are obvious staples for this population, but recovery could be a sea of great opportunity. Minding the transparency, "free from" and plant-based trends from the mainstream natural products market will be important to reaching these hardworking and demanding consumers. Sports Nutrition: Nutrients for Weekend Warriors/Active Consumers

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