Natural Products Insider

APR 2012

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Omega-3s, Vitamin A Slow Eye Disease Combining omega-3 essential fatty acids (EFAs) with vitamin A improved eye health for people who suffer from retinitis pigmentosa, a retinal disease that causes decreased night vision, loss of peripheral vision and, in advanced cases, loss of central vision (Arch Ophthalmol. 2012 Feb. 13. ePub ). Eliot L. Berson, M.D., of Harvard Medical School and the Massachusetts Eye and Ear Infirmary, Boston, and colleagues noted this is the first report that nutritional intake can modify the rate of decline of visual acuity in retinitis pigmentosa. The researchers analyzed dietary intake from questionnaires completed annually by 357 adult patients from three randomized trials who were all receiving 15,000 IU/d of palmitate vitamin A for four to six years. The time frame for the studies were from 1984 to 1991, 1996 to 2001 and 2003 to 2008. Results showed mean rates of decline of acuity were slower among those with high omega-3 intake; patients with a diet high in long-chain omega-3 fatty acids had a 40-percent slower average annual rate of decline in distance visual acuity than those with a diet low in those fatty acids. Researchers also noted the mean rate of decline in letters per year on Early Treatment Diabetic Retinopathy Study (ETDRS) distance acuity testing was 0.59 letters for patients receiving vitamin A with high omega-3 intake versus 1.00 letter for patients receiving vitamin A with low omega-3 intake over a four-to-six-year period. "A representative patient who starts receiving vitamin A by age 35 years and eats an omega-3-rich diet (i.e., one to two three-ounce servings of oily fish per week) with an ETDRS acuity of 50 letters (equivalent to 20/30 on the Snellen chart) would, on average, be expected to decline to an ETDRS acuity of 24 letters (equivalent to 20/100 on the Snellen chart) at age 79 years, whereas this patient receiving vitamin A with a low dietary omega-3 intake (e.g. less than one three-ounce serving of oily fish per week) would decline to this level at age 61 years," the researchers concluded. VIRGO Debuts New INSIDER Website VIRGO unveiled a new website for Natural Products INSIDER featur ing design and architectural changes. The premium content, along with the latest news, is now framed individually in INSIDER's "carousel," the most prominent element in the editorial content area of the website, at the top center of the page. The premium content includes: r 3FQPSUT r (BMMFSJFT FYBNJOF TQFDJGJD NBKPS JTTVFT af fecting the industry; delivered as free downloadable PDFs) 4MJEF 4IPXT BOE *NBHF (BMMFSJFT allow the user to get quick information of the major issues and trends) r -JCSBSZ BSDIJWFE DPOUFOU UP BOTXFS UIF NPTU pressing questions) r %JTDVTTJPO XIFSF FYQFS UT BOE UIPVHIU leaders discuss, debate and define issues affecting the industry) NSIDER also added a bot tom navigation bar that gives the user another easy way to access premium content. This bar includes links to INSIDER's RSS feed, Facebook page and Twitter account. 10 INSIDER ¥ APRIL 2012 IN THE NEWS

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