Natural Products Insider

NOV-DEC 2016

INSIDER is the leading information source for marketers, manufacturers and formulators of dietary supplements, healthy foods and cosmeceuticals. Since 1997, INSIDER has been serving the needs of the global nutrition industry.

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40 INSIDER November/December 2016 INSIDER's Take According to the Centers for Disease Control and Prevention (CDC), about 610,000 people die in the United States every year due to heart disease, the leading cause of death for both men and women; however, research shows natural ingredients can help contribute to a heart healthy life. When thinking of heart health, some current popular ingredients for promoting a healthy heart include coenzyme Q10 (CoQ10), phytosterols, omega-3 fatty acids and tocotrienols. All of these ingredients are supported by science, according to CheeYen Lau, nutritionist, ExcelVite Inc. In addition, vitamin K2 has been indicated in protecting arterial function, inhibiting calcium from depositing. Foods such as almonds have been shown to contribute to heart protection because they are low in saturated fat and contain other protective nutrients. "Replacing saturated fats with plant-based or unsaturated fats like monounsaturated and polyunsaturated fats may help lower heart disease risk factors," said Jeff Smith, director of marketing, Blue Diamond Almonds Global Ingredients Division. Other heart healthy ingredients include fi ber, cocoa fl avanols, and minerals such as calcium and potassium. Certain minerals, such as calcium, have been shown to help heart health. A study published in the Journal of the American Heart Association indicated people with the highest total calcium intake from both food and dietary supplements had the lowest risk of coronary artery calcifi cation, according to Duffy MacKay, N.D., senior vice president, scientifi c and a regulatory affairs, Council for Responsible Nutrition (CRN). 1 "This confi rms the safety of calcium supplementation for heart health, which has been the conclusion of several large studies in recent years," MacKay said. "Consumers should have confi dence in the safety of calcium supplements, and women in particular should be aiming to get the targeted daily amount of calcium through a combination of diet and supplementation." In addition, "Many scientists have found signifi cant and independent associations between high dietary calcium intakes and lower blood pressure," said Sandra Gillot, CEO, Benexia. "Dietary calcium is an important factor for blood pressure via its effect on calcium metabolism." She noted calcium can be found in many fortifi ed foods and beverages, via the use of ingredients such as chia. Another mineral important for heart health is potassium, an electrolyte that works to regulate the balance of body fl uids. One study indicated high salt intake increased blood pressure, which in turn can play a role in cardiovascular disease (CVD). 2 Potassium was shown to attenuate these effects, demonstrating a potential link to reduction in stroke rates and CVD risk. It has been shown that within the United States, many people get more sodium than is recommended, which is its own independent risk factor for CVD. The study suggested a diet that increases potassium intake can decrease cardiovascular morbidity and mortality. Another study found potassium reduced both systolic and diastolic blood pressure. 3 It was discovered that, contrary to sodium, many Americans do not get the recommended amount of potassium in their diet. One strategy to increase potassium intake is the use of modifi ed salt, which means during food preparation, the sodium chloride is replaced by potassium chloride, offering a double advantage of decreasing sodium and increasing potassium intake. When it comes to heart health ingredients, the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are consistently among the most popular dietary supplements for heart health in the United States, according to the Survey of Vitamin & Supplement Users, 2016. In addition, researchers found in a 2013 meta-analysis that intake of omega-3 fatty acids is benefi cial for the maintenance of cardiovascular health in subjects with a history of CVD. 4 Marine sources of omega-3 fatty acids, such as fi sh and algae, have been shown to reduce triglyceride levels, which can lower the risk for heart disease, as triglycerides are a type of fat in the blood. Another way to obtain omega-3 fatty acids is through chia seeds and oil, Gillot said. "' Superfoods' are experiencing a boom in the consumer market because they are attractive and nutritive, and they are associated with multiple health benefi ts," she noted. Minerals such as calcium and potassium have been shown to support heart health. Current popular ingredients for promoting a healthy heart are CoQ10, phytosterols, omega-3 fatty acids, vitamin K2 and tocotrienols. Oil- and fat-soluble ingredients can pose a challenge during the formulation process, as they can be poorly absorbed. Heart Healthy Ingredients by Courtney Johnson Heart Health

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