Natural Products Insider

SEP-OCT 2017

INSIDER is the leading information source for marketers, manufacturers and formulators of dietary supplements, healthy foods and cosmeceuticals. Since 1997, INSIDER has been serving the needs of the global nutrition industry.

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SupplySide West Dietary intake has been shown on a molecular level to mitigate infl ammation, promote healthy aging, reduce the risk of cardiovascular disease, support bone maintenance, modulate lipid metabolism, change insulin sensitivity and infl uence the microbiome. Many promising phytonutrients, vitamins and minerals have already demonstrated potential benefi ts beyond their well-known, functional contribution to metabolic processes. For polyphenolics like resveratrol, their renowned antioxidant activity may just be the tip of the proverbial iceberg. It has long been recognized that the benefi ts of resveratrol cannot be explained by its antioxidant value alone, and emerging research suggests resveratrol may also exert epigenetic infl uence by blocking or inducing specifi c transcriptional effects. The convergence of nutrigenetics, nutrigenomics, metabolomics and epigenetics holds the promise of meaningful interventions that will personalize nutritional recommendations based upon genetic predispositions, gene expression reprogramming and imprinting, inherited diseases or disadvantages, lifestyle choices, lifestyle diseases, stages of life, behavioral challenges, environmental exposure and organoleptic preferences. The science may seem complex and even esoteric to the consumer, and yet consumers are easily able to understand and even embrace the truth that we are each different. It is human nature to want to be recognized and treated as special for those differences. The European Union's (EU) Food4Me project validated this idea. Regardless of whether a personalized dietary regime was accompanied by specifi c genetic counselling, subjects were more likely to comply with and stay on a dietary recommendation during the course of six months if they believed it had been designed specifi cally for them. (Gene s Nutr. 2015;10:450) Compliance to any regimen is more likely to be successful if the benefi ts are noticeable. Personalized nutrition has the potential to revolutionize health care. It is an opportunity to intercede in disease before diagnosis, reprogram genetic destiny, and shift focus from broad-based population "standards of care" to tailored, nutritional modalities for the individual. Jennifer Cooper is the vice president of research and development (R&D) and quality at TCC (twinlab. com). Previously, she was at US Pharmacia—primarily focused in Poland and Eastern Europe—where she oversaw food supplements (natural products), traditional herbal medicines, medical devices and dermocosmetics. Prior fi rms include Dynova Laboratories and Twinlab. Cooper has experience managing all the technical functions for over-the- counter (OTC)/natural products distributed in the mass and specialty markets, including regulatory affairs, product formulating and testing, contract manufacturing, scientifi c and clinical research, intellectual property (IP) and quality assurance (QA). She has developed and brought to market more than 300 new products.

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