Natural Products Insider

SEP-OCT 2017

INSIDER is the leading information source for marketers, manufacturers and formulators of dietary supplements, healthy foods and cosmeceuticals. Since 1997, INSIDER has been serving the needs of the global nutrition industry.

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naturalproductsinsider . com 13 INSIDER's Take Brain health and liver health are emerging areas of interest for curcumin research. Curcumin's antioxidant and anti-inflammatory effects support its benefits in sports applications. Curcumin's effect on the inflammatory response is key to most of its varied health benefits. Supplements: Curcumin According to SPINS data, curcumin products saw growth across several positionings in 2015/2016, including infl ammation, joint health, immune health, heart health, cognitive health and more. Research is critical to expand the reach of curcumin's healthy effects, and fortunately, it is being conducted to support the benefi ts of curcumin across several health categories. Sports Nutrition A growing pool of scientifi c data supports the role of curcumin in sports recovery and performance. Cosimo Palumbo, sales area manager North America, Indena S.p.A., pointed to a 2007 publication as "one of the fi rst demonstrations of curcumin's effects on infl ammation and performance recovery following eccentric exercise-induced muscle damage." 1 The animal study sought to examine the effects of curcumin on infl ammation and recovery of running performance following downhill running in mice. Researchers concluded the results support the hypothesis that curcumin can reduce infl ammation and offset some of the performance defi cits associated with eccentric exercise-induced muscle damage. The positive results were confi rmed in a human trial published in 2014. 2 In the randomized, placebo-controlled, single-blind pilot trial, 20 healthy, male volunteers were randomized to receive curcumin (as Meriva ® , from Indena S.p.A.) at a dose of 1 g twice daily (equivalent to 200 mg curcumin) or placebo. Supplementation was started 48 hours before a downhill running test and was continued for 24 hours after the test for four days. The results showed subjects supplemented with curcumin reported less pain in the lower limb and less magnetic resonance imaging (MRI) evidence of muscle injury in the posterior or medial compartment of both thighs. Markers of muscle damage and infl ammation tended to be lower in the curcumin-supplemented group, with a signifi cant reduction of interleukin 8 (IL8) at two hours. Emerging Research Points to New Potential for Curcumin by Rachel Adams In a study of 11 male recreational athletes, the athletes underwent three double-blind administrations of Meriva, placebo and no supplementation, and completed a cycling exercise set at 95 percent lactate threshold. 3 The results were consistent with a better-than-usual scoring in the subjective assessment of psychological stress in the curcumin group. The study also showed modulation of infl ammatory markers. Brain Health Emerging research is uncovering the potential of curcumin to support the brain. "Current curcumin research is very diverse, but among the various strands, one can see a developing focus on the mechanistic analysis of the anti-infl ammatory, anti-protein-malfolding and cation-chelating effects of curcuminoids," said Paul Clayton, Ph.D., chief scientifi c advisor, GE Nutrients Inc., referencing pathologies in

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