Natural Products Insider

MAR-APR 2018

INSIDER is the leading information source for marketers, manufacturers and formulators of dietary supplements, healthy foods and cosmeceuticals. Since 1997, INSIDER has been serving the needs of the global nutrition industry.

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Time to power up ! 16 INSIDER March/April 2018 of upper respiratory tract infection (URTI) in healthy subjects. 16,17,18 In an in vitro study published in 2017, the inactivated probiotic Bacillus coagulans GBI-30, 6086 (Staimune™, from Ganeden/ Kerry) activated human immune cells and altered the production of both immune- activating and anti-infl ammatory cytokines and chemokines. 19 Of special importance, research noted, is the selective upregulation of the granulocyte colony- stimulating factor (G-CSF) growth factor involved in postinjury and postinfl ammation repair and regeneration. "This suggests that important immunogenic cell wall components, such as lipoteichoic acid, are undamaged after the inactivation and retain the complex benefi cial biological activities previously demonstrated for the cell walls from live B. coagulans GBI-30, 6086 (GanedenBC 30 , from Ganeden/Kerry) probiotic bacteria," researchers wrote. Heat-inactivated L. salivarius CECT 5713 prevented adhesion of Streptococcus mutans—a bacterial species involved in dental caries—to hydroxyapatite, according to a 2017 publication. 20 Researchers concluded the inactive bacteria could be used as a strategy to reduce salivary concentration of this oral pathogen. Sports Nutrition Recent research supports the role of probiotics in managing exercise-induced infl ammation and muscle damage. Bifi dobacterium breve BR03 and Streptococcus thermophilus FP4 reduced infl ammation and improved the infl ammatory response to exercise in a recent double-blind, randomized, placebo-controlled, crossover study of 16 healthy, resistance-trained men. 21 For the study, each participant consumed a probiotic capsule containing 5 billion microencapsulated live cells of B. breve BR03 and S. thermophilus FP4 or placebo daily for 21 days prior to performing a muscle-damaging exercise of elbow fl exors. Performance of elbow fl exors and a marker of infl ammation (interleukin-6 [IL-6]) were measured prior to and following the exercise. Probiotic consumption attenuated performance and range-of-motion (ROM) decrements following muscle-damaging exercise. The probiotics also reduced baseline infl ammation and improved infl ammatory response to exercise. In a double-blind, randomized, placebo-controlled study of 23 collegiate female athletes, a strain of Bacillus subtilis (as DE111 ® , from Deerland Enzymes) had signifi cant effects on body composition and athletic performance when consumed along with adequate post-workout nutrition. 22 The athletes completed the same 10-week resistance training program during offseason, which consisted of three to four workouts per week of upper- and lower-body exercises and sport-specifi c training. The athletes consumed DE111 or placebo supplement in conjunction with a recovery protein drink immediately following resistance and sport-specifi c training for the entire 10-week program. T i me t o p ow e r u r p ! www.nexira.com info-usa@nexira.com ViNitrox ª is a unique and proprietary synergistic combination of apple and grape polyphenols. It has been specifically developed to answer the demands of athletes in search of natural dietary supplements. ViNitrox ™ offers a number of exceptional sports nutrition properties including enhanced and lasting performance. Nexira's latest clinical study on 50 athletes, 25-45 years old, demonstrated that under intensive effort 500 mg/day of ViNitrox ™ improves physical capabilities. PUBLISHED CLINICAL STUDY Ignite muscle performance Break through the fatigue barrier Amp up Nitric Oxide level Apple & grape polyphenols e r u p ! VISIT US AT BOOTH D129 Supplements: Probiotics

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