Natural Products Insider

MAR-APR 2018

INSIDER is the leading information source for marketers, manufacturers and formulators of dietary supplements, healthy foods and cosmeceuticals. Since 1997, INSIDER has been serving the needs of the global nutrition industry.

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30 INSIDER March/April 2018 cherry's effectiveness is its spectrum of plant compounds. "The majority of the Montmorency tart cherry materials on the market are either from juice or skins (waste stream of the juicing process), claiming a high level of total anthocyanins, but missing the complete phytonutrient profi le from its whole food," he said, adding VitaCherry Sport is a full-spectrum ingredient containing the key anti-infl ammatory phytonutrients. "These anti-infl ammatory markers naturally exist in a much higher concentration when in a whole food matrix." A proprietary blend of polyphenols from tea (Camellia sinensis) may help limit post-exercise damage from infl ammation. XSurge™, from Kemin Health, contains catechins, theafl avins, caffeine and manganese, and has been shown to limit the pro-infl ammatory cytokine interleukin-8 (IL-8) response to exercise. 15 Subsequent research found four weeks of XSurge supplementation, compared to placebo, increased total antioxidant capacity and limited muscle power loss following acute damaging resistance exercise in untrained men. 16 Strength adaptations from six weeks of resistance training were unhindered by supplementation. The carotenoid astaxanthin, derived commercially from the microalgae Haematococcus pluvialis, may inhibit free radical production and related antioxidant declines following competitive exercise, according to a 2012 trial of elite soccer players. 17 Specifi cally, astaxanthin supplementation lowered post-exercise levels of free radicals such as superoxide, as well as muscle damage markers, including creatine kinase (CK). Astaxanthin might also improve overall stress and fatigue, including mental fatigue, following both mental and physical challenges. 18 The research highlighted improved clarity, concentration, motivation and mood, as well as reduced physical heaviness and irritation. Probiotics are well known for digestive benefi ts, but at least one specifi c strain, Bacillus coagulans GBI-30, 6086, has shown various muscle protective benefi ts. This spore-forming probiotic (as GanedenBC 30® , from Ganeden), when combined with protein intake, decreased muscle damage as marked by CK and blood urea nitrogen (BUN) levels. 19 GanedenBC 30 may also improve amino acid digestion when taken with protein, including the plant proteins pea, soy and rice. 20,21 When taken with β-hydroxy-β-methylbutyrate (HMB) calcium, GanedenBC 30 controlled infl ammation response to intense military training more than HMB calcium alone. 22 (Turn to page 12 for more probiotic research in numerous areas of health.) The brain's effect on exercise and muscles is an overlooked, but emerging, area of sports nutrition. The brain controls muscle movements during exercise, and cerebral blood fl ow is a limiting factor of high-intensity exercise. Deep Ocean Minerals (DOM ® , from CK Nutraceuticals) contains desalinated minerals and trace elements that improve cerebral hemodynamic response to exercise, according to a study of exercise recovery in middle- aged men. 23 The omega-3 fatty acid docosahexaenoic acid (DHA) is a building block of the brain and plays a prominent role, along with the omega-3 eicosapentaenoic acid (EPA), in anti- infl ammatory pathways. These essential fatty acids produce anti-infl ammatory signaling compounds including resolvins (Rvs), maresins and protectins. A study of soccer players taking a DHA-enriched beverage for eight weeks demonstrated the omega-3 worked synergistically with exercise to increase the anti-infl ammatory cytokine prostaglandin E1 (PGE1), as well as resolvin D1. 24 Omega-3 fatty acids may also infl uence muscles' metabolic response to nutrition and functional response to exercise due to anti-infl ammatory actions and possibly lipid remodeling. 25 Resolvin D1 manages infl ammatory cytokines and oxidative stress that contribute to joint problems associated with osteoarthritis (OA), a wear-and-tear joint problem similar what athletes suffer from after years of exercise, especially on hard surfaces. 26 Many joint health anti-infl ammatory ingredients have made appearances in sports nutrition recovery formulations, such as glucosamine, chondroitin and hyaluronic acid. While the popular tandem glucosamine and chondroitin have had mixed results in large controlled trials, adding a calcium fructoborate complex (as FruiteX-B ® , from FutureCeuticals) shores up joint health benefi ts, reducing pain and function symptoms by around 25 percent in one study. 27 On its own, 110 mg FruiteX-B twice daily for two weeks improved knee discomfort in adults with self-reported knee discomfort. 28 Specialty joint ingredients with potential for recovery products includes natural eggshell and egg membrane, which contains glycosaminoglycans (GAGs) found in synovial joints such as the knee, elbow and shoulder. Sports Nutrition: Recovery

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